Iran Air Flight 655

Wikipedia:

Iran Air Flight 655 was a scheduled passenger flight from Tehran to Dubai via Bandar Abbas, that was shot down on 3 July 1988 by an SM-2MR surface-to-air missile fired from USS Vincennes, a guided missile cruiser of the United States Navy. The aircraft, an Airbus A300, was destroyed and all 290 people on board, including 66 children, were killed. The jet was hit while flying over Iran’s territorial waters in the Persian Gulf, along the flight’s usual route, shortly after departing Bandar Abbas International Airport, the flight’s stopover location. Vincennes had entered Iranian territory after one of its helicopters drew warning fire from Iranian speedboats operating within Iranian territorial limits.

The Washington Post, April 23, 1990:

The Navy has awarded special commendation medals for “meritorious service” to two of the top officers who were serving on the USS Vincennes at the time the cruiser shot down an Iranian airliner over the Persian Gulf with 290 people aboard.

The citations for the special commendations to former Vincennes skipper Capt. Will Rogers III and Lt. Cmdr. Scott E. Lustig, who was the ship’s weapons and combat systems officer, do not mention the downing of the aircraft on July 3, 1988, an error that took the lives of the plane’s passengers and crew.

The Washington Post, January 9, 2020:

On Saturday, President Trump invoked history when tweeting out a threat to destroy “52 Iranian sites … some at a very high level & important to Iran & the Iranian culture.” He said the potential targets represent the 52 Americans who were held hostage there for 444 days from 1979 to 1981.

Though the incident is nearly forgotten in the United States, it is etched deeply in memory in Iran, where the country is mourning the U.S. airstrike that killed Iranian military commander Qasem Soleimani.

So there’s that.